NSF Director Steps Down Amid Layoffs and Budget Cuts

On April 24, 2025, National Science Foundation (NSF) Director Sethuraman “Panch” Panchanathan announced his resignation in a letter obtained by multiple outlets. The decision comes as the agency faces an unprecedented 55% cut to its $9 billion annual budget and plans to lay off approximately half of its 1,700-person workforce.
Background: Budget Cuts and Organizational Upheaval
The Trump administration’s fiscal 2026 proposal slashes NSF’s appropriation from $9 billion to roughly $4.05 billion. To align with the reduced funding, NSF plans to eliminate 850 positions and cancel over 400 active grants—valued at nearly $1 billion—that are deemed “non-core.” Programs in environmental justice, misinformation studies, and diversity in STEM are among those most impacted.
- Staff Reduction: ~850 roles eliminated across directorates for Biological Sciences, Engineering, Geosciences, and Computer & Information Science & Engineering.
- Grant Cancellations: 400+ awards terminated; principal investigators notified with a 60-day wind-down period.
- Operational Efficiency: Bid to apply DOGE (Department of Government Efficiency) protocols, led by Elon Musk appointees embedded since April 14.
Impact on AI & Machine Learning Programs
NSF currently funds 23 regional AI research institutes through a $500 million, five-year initiative. The cuts jeopardize at least 12 institutes mid-contract, disrupting research in federated learning, autonomous systems, and AI for social good. Dr. Jane Rogers, former NSF AI program director, warns that “losing these nodes will fragment the national AI ecosystem and erode collaborative frameworks enabled by cloud-to-edge testbeds.”
Disruption to HPC and Infrastructure
NSF supports three major supercomputing centers—XSEDE, ACCESS, and Frontera—delivering over 2.5 petaflops of shared computing capacity. The revised budget foresees a 40% reduction in HPC allocations, delaying hardware refresh cycles for GPU-accelerated systems (NVIDIA A100, AMD MI250) and threatening the rollout of next-generation exascale collaborations with DOE.
Policy and Congressional Response
In response, Senate Science Committee Chair Maria Cantwell introduced the NSF Restoration Act (S.1234) on May 2, 2025, aiming to block the proposed cuts. A bipartisan group of 45 representatives issued a letter urging President Biden to exercise his line-item veto or push a supplemental appropriation. Meanwhile, the White House Office of Science and Technology Policy (OSTP) signals support for preserving foundational research budgets.
Forward-Looking Analysis
With 16 months remaining in Panchanathan’s term, Deputy Director Mary Sue Coleman will step in as acting director. Experts anticipate a strategic pivot to secure alternative funding through public-private partnerships and augmented collaboration with agencies like DOE, NIH, and DARPA. Congressional hearings scheduled for June 2025 will further scrutinize DOE-driven DOGE interventions.
Expert Opinions and Recommendations
- Dr. John Smith, former NSF policy analyst, recommends establishing an emergency research continuity fund to buffer critical AI and HPC programs.
- Industry consortium leaders advocate for a “rescued grant” model, enabling tech companies to co-fund NSF-approved projects and maintain research momentum.